10ème Colloque Annuel du GRASP - Lundi 20 Novembre 2017 10th Annual GRASP Symposium - Monday, November 20, 2017 8h00

Ouverture du Bureau d’Inscription / Registration Desk Opens Entrée Salle de Bal / Ballroom Lobby

8h00-8h45

Installation des Affiches / Poster Set-up Café & Croissants avec les Exposants / Coffee & Croissants with Exhibitors Salle de Bal / Ballroom

Salle de Bal / Ballroom A

Séance 1 / Session 1

8h45-9h00

Mots d’Ouverture / Opening Words – Kalle Gehring, McGill University

9h00-9h30

Frédéric Allain, ETH Zurich – Switzerland Hybrid structural approaches to solve structures of protein-nucleic acid complexes Présenté par / Introduced by Khanh Huy Bui, McGill University

9h35-10h05

Mei Hong, Massachusetts Institute of Technology – USA Structural basis of viral fusion and budding: cholesterol binding and membrane curvature generation by proteins Présentée par / Introduced by Nicolas Doucet, INRS

10h10-10h35

Pause Santé avec les Exposants / Health Break with Exhibitors

10h35-11h05

Philip Chamberlain, Celgene – USA Structural basis for ligand-directed degradation by the CRL4CRBN E3 ubiquitin ligase Présenté par / Introduced by Jean-François Trempe, McGill University

Salle de Bal / Ballroom A

Séance 2 / Session 2

Sous la Présidence de / Session Chair: Edna Matta-Camacho, McGill University 11h15-11h27

Timon Geib, UQAM Absolute quantitation of acetaminophen-modified HSA by LC-MS/MS

11h30-11h42

Aman Garg, McGill University Agent based modeling of surgical vocal fold injury and repair

11h45-11h57

Leila Mousavifar, UQAM Family of monovalent mannopyranoside analogs potential therapeutic candidates for inhibition of the E. Coli FimH adhesion

12h00-12h12

Robert Harkness, McGill University Elucidating the pathways of supramolecular assembly by thermal hysteresis

12h15-12h27

William Copp, Concordia University Influence of nucleotide modifications at the C2’ position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA

Salle du Parc / du Parc Room

Séance 3 / Session 3

Sous la Présidence de / Session Chair: Luciana Coutinho de Oliveira, Université de Montréal 11h15-11h27

Jaeok Park, McGill University Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product: implications for drug discovery

11h30-11h42

Aurélien Fouillen, Université de Montréal Impact of bacteria associated with periodontal diseases on the attachment matrix of the gingival seal

11h45-11h57

Camille Marie Fortinez, McGill University Structural and functional investigations of the biosynthetic pathway for bacillamide, a thiazole-containing natural product

12h00-12h12

Charline Mary, Université de Montréal Analysis of the role of the interaction of VirB6 with VirB10 in Type IV secretion systems

12h15-12h27

Lena Moeller, Université de Montréal Stoichiometry of Kv2.1/Kv6.4 heterotetramers revealed by fluorescent single channel subunit counting

12h30-13h30

Diner (Buffet avec les Exposants) / Lunch (Buffet Style with Exhibitors)

Salle de Bal / Ballroom A

Séance 4 / Session 4

13h30-14h00

Mirek Cygler, University of Saskatchewan – Canada Structure, function and dynamics of the mitochondrial Fe/S cluster synthesis complex Présenté par / Introduced by Kalle Gehring, McGill University

14h05-14h35

Juha Huiskonen, University of Oxford – United Kingdom Insight into viral class II membrane fusion activation by a combined structural biology approach Présenté par / Introduced by Khanh Huy Bui, McGill University

14h40-15h10

Joaquin Ortega & Kalle Gehring, McGill University Presentation of the structural biology equipment platforms

Salle de Bal / Ballroom A

Séance 5 / Session 5

Sous la Présidence de / Session Chair: Chitra Narayanan, INRS Armand Frappier 15h15-15h27

Jonathan Labriola, McGill University A leucine residue facilitates substrate recognition in the Salmonella bacterial effector AvrA

15h30-15h42

Mathew Sebastiao, UQAM Microplate assays of amyloid self-assembly are more sensitive than previously thought: a cautionary tale regarding experimental parameters

15h45-15h57

Richard Lincoln, McGill University Mitochondria alkylation and cellular trafficking mapped with a lipophilic BODIPY–acrolein fluorogenic probe

Salle du Parc / du Parc Room

Séance 6 / Session 6

Sous la Présidence de / Session Chair: Normand Cyr, Université de Montréal 15h15-15h27

Oleg Matusovsky, McGill University High-speed AFM imaging revealed differences in the structure of blocked and closed states of native cardiac thin filaments.

15h30-15h42

Ryan Killoran, Université de Montréal Real-time monitoring of GTPase activity and signaling using NMR spectroscopy

15h45-15h57

Kathy Wong, McGill University Structural mimicry by a bacterial F Box effector hijacks the host ubiquitin-proteasome system

Salle de Bal / Ballroom A and B 16h00-18h30

Séance 7 / Session 7

Salon des Affiches & Salon des Exposants / Poster Pub & Exhibition Area Open Présentation des Prix & Remerciements / Presentation of Awards & Closing Words Kalle Gehring, McGill University