8ème Colloque Annuel du GRASP - Lundi 23 Novembre 2015 8th Annual GRASP Symposium - Monday, November 23, 2015 8h00

Ouverture du Bureau d’Inscription / Registration Desk Opens Entrée Salle de Bal / Ballroom Lobby

8h00-8h45

Installation des Affiches / Poster Set-up Café & Croissants avec les Exposants / Coffee & Croissants with Exhibitors Salle de Bal / Ballroom

Salle de Bal / Ballroom A

Séance 1 / Session 1

8h45-9h00

Mots d’Ouverture / Opening Words – Martin Schmeing, McGill University

9h00-9h30

Poul Nissen, Aarhus University – Aarhus – Denmark Structure and mechanism of ion pumps and secondary transporters Présenté par / Introduced by John Silvius, McGill University

9h35-10h05

Wei Yang, National Institutes of Health – Bethesda - USA Structural views of macromolecular machines on DNA biology Présentée par / Introduced by James Omichinsky, University of Montreal

10h10-10h22

Charles Pemble, Rigaku Americas Corporation Integrated Rigaku Systems: Tools for Structural Biology Success.

10h25-10h55

Pause Santé avec les Exposants / Health Break with Exhibitors

10h55-11h25

Adrian Ferré d’Amaré, National Institutes of Health – Bethesda - USA Crystal structure of an RNA mimic of GFP reveals a G-quadruplex core Présenté par / Introduced by Lekha Sleno, UQAM

Salle de Bal / Ballroom A

Séance 2 / Session 2

Sous la Présidence de / Session Chair : Michael Tarry, McGill University 11h30-11h42

Jacinthe Gagnon, INRS-Armand Frappier Crystal structure and biophysical characterization of RNases 4 and 6, members of the human RNase A superfamily

11h45-11h57

Kristjan Bloudoff, McGill University Chemical probes allow structural insight into the condensation reaction of nonribosomal peptide synthetases

12h00-12h12

David Bernard, INRS-Armand Frappier Evolution of conformational exchange in the ribonuclease 3 subfamily

12h15-12h27

Janice Reimer, McGill University Crystal structures of the initiation module of a formylating nonribosomal peptide synthetase show its elegant synthetic cycle

Salle du Parc / du Parc Room

Séance 3 / Session 3

Sous la Présidence de / Session Chair : Maïwenn Beaugrand, McGill University 11h30-11h42

Carlos G. Oliver, McGill University

Addition of negative charge through mutation of an evolutionarily conserved tyrosine residue induces global, concerted millisecond timescale dynamics in the intrinsically disordered carboxyl terminus of γtubulin 11h45-11h57

Julie Briot, Université de Montréal Towards the structural characterization of the cache_VGCC domain within the voltage gated calcium channel CaVα2δ auxiliary subunit

12h00-12h12

Radu Gabriel Avramescu, McGill University Structural cues contributing to CFTR downregulation by VX-770, a gating potentiator drug

12h15-12h27

Saud Ayed, University of Ottawa Investigation of the functional role of conformational changes in the MinE bacterial cell division protein

12h30-13h30

Diner (Buffet avec les Exposants) / Lunch (Buffet Style with Exhibitors)

Salle de Bal / Ballroom A

Séance 4 / Session 4

13h30-14h00

Jeffrey Kieft, University of Colorado & Howard Hughes Medical Institute –Aurora - USA Structural viral RNAs: manipulators and exploiters of the cellular machinery Présenté par / Introduced by Khan Huy Bui, McGill University

14h05-14h35

Antonina Roll-Mecak, National Institutes of Health – Bethesda - USA How microtubules get their spots: insights from structural studies of tubulin modification enzymes Présentée par / Introduced by Bhushan Nagar, McGill University

14h40-14h52

Nicolas Doucet, INRS-Armand Frappier How to write a good paper.

14h55-15h07

Kalle Gehring, McGill University How to do good statistics.

Salle de Bal / Ballroom A

Séance 5 / Session 5

Sous la Présidence de / Session Chair : Jaeok Park, McGill University 15h10-15h22

Bastien Casu, Université de Montréal TraE from the pKM101 type IV secretion system forms promiscuous dimers and is specifically inhibited by small molecules derived from inhibitors of Brucella VirB8

15h25-15h37

Yazan Abbas, McGill University Structural and evolutionary insights into domain-swapping mechanisms within the antiviral IFIT2 and IFIT3 proteins

15h40-15h52

Mahzad Sharifahmadian, Université de Montréal Interactions and functions of VirB8 and VirB10 in type IV secretion systems

15h55-16h07

Diego Alonzo, McGill University In-vitro reconstitution of a macromolecular machine (and some hints on its structure)

Salle du Parc / du Parc Room

Séance 6 / Session 6

Sous la Présidence de / Session Chair : Patrick Kim Chiaw, McGill University 15h10-15h22

David Becerra, McGill University Predicting protein folding pathways of proteomes using ensemble modelling and genomic variations

15h25-15h37

Marta Vranas, McGill University The structural basis for Parkin-mediated mitochondrial quality control: implications for Parkinson’s disease

15h40-15h52

Samaneh Dastpeyman, Concordia University Heme tracking of a yeast mitochondrial peroxidase using fluorescence lifetime measurements

15h55-16h07

Yogita Patel, McGill University Characterization of Hsp70 inhibitors

Salle de Bal / Ballroom A and B 16h10-18h30

Séance 7 / Session 7

Présentation des Prix & Remerciements / Presentation of Awards & Closing Words - Kalle Gehring Salon des Affiches & Salon des Exposants / Poster Pub & Exhibition Area Open