7ème Colloque Annuel du GRASP ‐ Lundi 24 Novembre 2014 7th Annual GRASP Symposium ‐ Monday, November 24, 2014
8h00
Ouverture du Bureau d’Inscription / Registration Desk Opens Entrée Salle de Bal / Ballroom Lobby
8h00‐8h45
Installation des Affiches / Poster Set‐up Café & Croissants avec les Exposants / Coffee & Croissants with Exhibitors Salle de Bal / Ballroom
Salle de Bal / Ballroom A
Séance 1 / Session 1
8h45‐9h00
Mots d’Ouverture / Opening Words – Rose Goldstein, Vice‐Principal, McGill University Présentée par / Introduced by Kalle Gehring, GRASP Director, McGill University
9h00‐9h30
Werner Kühlbrandt, Max‐Planck Institute – Frankfurt – Germany What X‐rays cannot do: the resolution revolution in cryo‐EM Présenté par / Introduced by Martin Schmeing, McGill University
9h35‐10h05
Cynthia Wolberger, Johns Hopkins University – Baltimore ‐ USA Mechanims for regulating histone H2B deubiquitination by the SAGA DUB module Présentée par / Introduced by Simon Wing, McGill University
10h10‐10h22 Angela Criswell, Rigaku Americas Corporation Revisiting S‐SAD data collection in the Home Lab: what you can do with copper radiation.
10h25‐10h55 Pause Santé avec les Exposants / Health Break with Exhibitors
10h55‐11h25 Helen Saibil, Birkbeck College – London – United Kingdom Machinery of membrane hole punchers in pathogen attack and immune defence Présentée par / Introduced by David Thomas, McGill University
Salle de Bal / Ballroom A
Séance 2 / Session 2
Sous la Présidence de / Session Chair : Fabien Bergeret, McGill University
11h30‐11h42 Meena Kathiresan, Concordia University Peroxidation of a heme‐ligated histidine triggers heme transfer between antioxidant enzymes in mitochondria
11h45‐11h57 Rory Sleno, McGill University A platform to capture ligand‐induced conformational rearrangement of GPCRs in live cells
12h00‐12h12 Aleksandr Sverzhinsky, McGill University Coordinated rearrangements between cytoplasmic and periplasmic domains of the membrane protein complex ExbB–ExbD of Escherichia coli
12h15‐12h27 Patrick Kim Chiaw, McGill University Assessing the role of Hsp70 on CFTR biogenesis
Salle du Parc / du Parc Room
Séance 3 / Session 3
Sous la Présidence de / Session Chair : Xinlu (Crystal) Li, McGill University
11h30‐11h42 Patricia Brown, McGill University Kainate receptor heteromerization and auxiliary proteins relieve channel block by facilitating polyamine permeation
11h45‐11h57 Marianne Ngure, McGill University, University of Alberta Characterization of complexes of HCV NS5ADII and CypA with and without RNA
12h00‐12h12 Mikaël Bédard, Université de Sherbrooke Structural biology of Miz‐1 zinc fingers by liquid state NMR
12h15‐12h27 Janice Reimer, McGill University Structural insights into a novel formylation domain found in the linear gramicidin NRPS
12h30‐13h30 Diner (Buffet avec les Exposants) / Lunch (Buffet Style with Exhibitors)
Salle de Bal / Ballroom A
Séance 4 / Session 4
13h30‐14h00 Khanh‐Huy Bui, European Molecular Biology Laboratory – Heidelberg ‐ Germany Integrated structural analysis of the human nuclear pore complex scaffold Présenté par / Introduced by Isabelle Rouiller, McGill University
14h05‐14h35 Andreas Martin, University of California at Berkeley ‐ Berkeley ‐ USA Grab, pull, and cut: mechanisms of protein degradation by the 26S proteasome Présenté par / Introduced by Jean‐François Trempe, McGill University
14h40‐14h52 Paul Belcher, GE HealthCare To affinity and beyond: from screened hits to optimized leads with SPR
14h55‐15h07 Maïwenn Beaugrand, Université du Québec à Montréal – Montreal ‐Canada Bionano Exchanges Présentée par / Introduced by Kalle Gehring, McGill University
Salle de Bal / Ballroom A
Séance 5 / Session 5
Sous la Présidence de / Session Chair : Shafqat Rasool, McGill University
15h10‐15h22 Benedeta Hasaj, Concordia University TRAMM is a moonlighting protein that functions in chromosome congression, kinetochore stability and CENP‐E recruitment
15h25‐15h37 Jason Harris, McGill University Milli‐microsecond timescale dynamics in the flexible C‐terminus of yeast γ‐tubulin
15h40‐15h52 Xinlu (Crystal) Li, McGill University Probing the nucleotide‐binding properties of HEPN by fluorescence polarization assays
15h55‐16h07 Mohamed Kodiha, McGill University Quantitative microscopy reveals remodelling of nucleoli by pharmacological activators of AMPK
Salle du Parc / du Parc Room
Séance 6 / Session 6
Sous la Présidence de / Session Chair : Daniel Calles, McGill University
15h10‐15h22 Janane Rahbani, McGill University Stimuli‐responsive DNA nanotubes
15h25‐15h37 Lauriane Lecoq, Université de Montréal Structural characterisation of the complex between the transactivation domain of p65 and the Tfb1/p62 subunit of TFIIH transcription factor
15h40‐15h52 Filip Liebsch, McGill University The beta‐site APP‐cleaving enzyme 1 (BACE1) exists naturally as trimers and has a function in copper homeostasis
15h55‐16h07 Brahm J. Yachnin, McGill University The structural basis for BVMO substrate profile and stereospecificity
Salle de Bal / Ballroom A and B
Séance 7 / Session 7
16h10‐18h30 Présentation des Prix & Remerciements / Presentation of Awards & Closing Words ‐ Kalle Gehring Salon des Affiches & Salon des Exposants / Poster Pub & Exhibition Area Open