49 IVS patients from 4 PET centers (Créteil n=15; Dijon n=14; Cuneo n=11; Rouen n=9)
PET/CT at baseline and 2 cycles Interpretation by 3 observers using the 5PS Transfers/readings on Positoscope workstations Inter-observer agreement (Kappa)
Quantification with ∆SUV (66% cut-off)
5-point scale weighted Kappa (Cohen)
Landis and Koch scale 66%) Event-free survival
n=36
n=36
# of events = 14 Median f-u = 25 mo
n=13
P = .003 χ2 = 8.97 n=36
Créteil : 2-y EFS : 81% vs. 46%
n=13
P = .002 χ2 = 9.42 Dijon : 2-y EFS : 81% vs. 45%
→ Better agreement between observers
n=13
P = .002 χ2 = 9.96 Cuneo : 2-y EFS : 81% vs. 45%
Conclusions
5PS: moderate to substantial agreement (κ 0.58-0.61) Ref. background must be high for interim PET/NHL Subjectivity → need for different opinions foci that were considered by Créteil/Dijon as “moderately increased above liver” (4) were considered “equal to liver” (3) by Cuneo
Quantification may help the definition of scores 3-4 ∆SUV is not observer-dependent for EFS prediction
PET Interpretation Issues: Quantitative Analysis. (Problems and Reproducibility) .... Patient preparation. â Scanner calibration. â Data acquisition. â Data analysis.
challenging with respect to Good Manufacturing Practice (GMP) compliancy. ⢠2-step synthesis (Perk L. et al, Eur J Nucl Med Mol Imaging (2010) 37:250â259.).
Staging and risk assessment of marginal zone lymphoma: ââ¦The value of positron emission ... MALT originating from the left lacrimal gland. PET-CT in MALT ...
if + (scores 4-5) or equivocal (score 3) then PET after 2 ABVD cycle. ⢠N=199 HL. 54 I-IIA .... Baseline MTV predictive of PFS and OS although tumor bulk was not.
...represents... ...evokes.... I agree with the artist because I feel .... I don't agree with the message given in this painting. In fact,... The artist wanted to show that.
3 Principal layout ... chart is delivered as a PDF file using vector graphics which has the advantage ... vertical axes form a grid which is shown in light dots. ... In meteorology, a cloud is a visible mass of liquid droplets or frozen crystals made
For the pair production, at first, the following mass correlation is necessary: 2. 2cme p. â¥Îµ. (where p ..... will name the spinning semi-photons (see Appendix 1). 3.3. ...... which acts in opposite direction to the Coulomb's electric force, appea
Jan 19, 2009 - patient's menstrual cycle, which had a rather constant length of 23 days .... spheroplast-L-form variants, Infection, May-Jun;24(3):218-26, 1996.
At third, it is not difficult to calculate the components value .... r Ï Ï Ï =ââ â. ,. (4.6). Using the quantum form of U and S o. : ÏÎ±Ï Ï. 0. Ë. 8. 1. + ..... the circle length,.
Here we continue the electron structure study. Since the Dirac equation ... A.4 Quantum of magnetic flow of the ring model electron. Conclusion. References ... of the particle, which has the electromagnetic field, photon is able to move along the ...
tailplane and fins in pre-cut, decorated sheet balsa. ... GEMINI. Duration model with all fuselage ... Type 2 Flying Boat,. Emily. ..... The "Heli' refers to the fact that its take-off and landing .... The last photo dramatically illustrates a typica
aspects of both male and female physiology, and at times their genital ...... www.pfc.org.uk/files/EngenderedPenalties.pdf and as referenced in European Union.
