R e fe re n c e Su p p o rt R e s u lts Me th o d G o a l In tro d u c tio n

Page 1 ... Ludwig, E. & Klingler, J. (1956) 'atlas humani cerebri', Basel, New. York, Karger, S. Peltier, J., Travers, N., Destrieux, C. & Velut, S. (2006), 'Optic ra-.
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FIBRATLAS : A novel method to visualize dissection of white matter tracts. Preliminary results

C Destrieux 1,2,3,4, I Zemmoura 1,2,3,4, B Serres 1,5, G Venturini 5, D Bourry 6, S Velut 2,4, F Andersson 3, JP Cottier 1,3,7

1: UMRS "Imagerie et Cerveau", INSERM U930, CNRS ERL3106, Université François Rabelais de Tours, Tours, France 2: Centre Hospitalier Régional Universitaire de Tours, Service de Neurochirurgie, Tours, France 3: Institut Fédératif de Recherche 135 "Imagerie Fonctionnelle", Tours, France 4: Université François Rabelais de Tours, Laboratoire d'Anatomie, Tours, France 5: Université François Rabelais de Tours, Laboratoire d'Informatique, EA2101, Tours, France 6: Université François Rabelais de Tours, Faculté de Médecine, Dpt. Com. et Multimédia, Tours, France 7: Centre Hospitalier Régional Universitaire de Tours, Service de Neuroradiologie, Tours, France

contact : [email protected]

Introduction

In Human, dissection (Klingler's method) gives access to white mater tracts anatomy It better preserves the 3D architecture of the specimen than techniques using slices

Goal

Dissection of a given tract destroys more superficial structures, making difficult the evaluation of relationships between fiber tracts and to cortex To develop a method providing accurate surface and texture representation of anatomical specimens during dissection of white mater tracts

2 Brains from body donation program

Specimens preparation

Fixation (5% formaldehyde, 8 weeks) -15°C, 4 weeks

Paraffin and fiducial markers

Fixation on holder

Method

Surface acquisition : 3D scanner laser (FARO Arm and Laser Line Probe

Klingler dissection

Geomagic software) Texture acquisition : Pentax K20 digital camera (Pentax DA Macro 35mm f/2.8 lens)

Texture acquisition

Surface acquisition Fiducial markers (Yellow arrow heads) are visible on both acquisitions Landmark (fiducial) based orthogonal projection

Texture projection onto surface

3D visualization software currently developped by Laboratoire d’Informatique de l’Université de Tours (OpenGL/Qt)

Combined to texture projection, it facilitates the recognition of white matter tracts This maybe used for educational purposes and for tracts reconstruction from dissections

General Electric Healthcare Institut Fédératif de Recherche, "Imagerie fonctionnelle" Société Française de Neurochirurgie

References

Support

Results

The laser acquisition allows interactive visualization of the dissected surface

Klingler, J. & Gloor, P. (1960), 'The connections of the amygdala and of the anterior temporal cortex in the human brain'. J Comp Neurol, vol. 115, 333-69. Ludwig, E. & Klingler, J. (1956) 'atlas humani cerebri', Basel, New York, Karger, S. Peltier, J., Travers, N., Destrieux, C. & Velut, S. (2006), 'Optic radiations: a microsurgical anatomical study'. J Neurosurg, vol. 105, 294-30.