It happened during a Michal 1 procedure Epigastric artery Papavérine
Clamp
2a
2b
2c The first intracavernous injection in february 1981
Early pionneers 1976-1980
In the meantime in Paris…
Group 1: « Non organic » Group 2: « Arterial » Group 3: « Venous and Mixed
Giles S Brindley 1983/ Phenoxybenzamine
Adrian W Zorgniotti 1983/ Papaverine-Phentolamine
« CERITINE » Papaverine Alphablockers Dipyramidole Atropine PGE1 J. of Urology 1991
11
Self IC injections of etilefrine
Over 7000 patients on Intracavernous Injections 7000 6000 5000
4000 3000 2000 1000 0
Total ICI
Ronald Virag CETI-Paris H.Sussman, P.Bouilly, C.Daniel, K.Shoukry, F.Nollet, C.Richard, J.Floresco, H.Saltiel, D.Frydman, C.Lévy Et Catherine Arnion Académie de Chirurgie~Séance du 5 mai 2010
Why do you prefer ICI ? Sure/ No performance anxiety Longer erections Stay after ejaculation Very few side effects
Diagnosis Treatment
Research
The Present
Pivotal role of IC pharma test
Oral ICI Surgery
Treatment of a symptom
Cure or Prevent a disease
Compounds mixing NO donnors + Calcium blockers + K channel openers Improvement of IC Routes Guided molecules Micropumps
• • •
•
VEGF ENDOTHELIAL GENE THERAPY ADIPOSE TISSUE STEM CELL THERAPY ICI OF STEM CELLS FROM THE NEURAL CREST
AUTOLOGOUS CELLULAR THERAPY
A new promising treatment for ED and Lapeyronie’s disease AUTOLOGOUS CELLULAR THERAPY
CETI
Traitement de la Maladie de Lapeyronie par PRP + HLA-
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